Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CHRNG | P07510 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955701 | 0.87 | HTR3A (0.47) | DDB1CRBNHTR3A | |
| SCHEMBL29952339 | 0.85 | — | — | |
| SCHEMBL21355057 | 0.83 | KDM4E (0.42) | KCNJ1DDB1CRBNKDM4EGLA | |
| SCHEMBL32684974 | 0.83 | KDM4E (0.42) | KCNJ1DDB1CRBNKDM4EGLA | |
| SCHEMBL29951949 | 0.83 | DDB1 (0.47) | DDB1CRBNKDM4EGLAHTT | |
| SCHEMBL26817536 | 0.81 | HTT (0.49) | KCNJ1DDB1CRBNKDM4EGLA | |
| SCHEMBL2559816 | 0.77 | PARP1 (0.33) | KCNJ1 | |
| SCHEMBL2562746 | 0.77 | PARP1 (0.33) | KCNJ1 | |
| SCHEMBL24666229 | 0.76 | KCNJ1 (0.33) | KCNJ1KDM4EGLAHTTKMT2A | |
| SCHEMBL24323731 | 0.76 | F2R (0.38) | KCNJ1KDM4EGLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |