Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20330598 | 1.00 | ERN1 (0.44) | ERN1TYRTRIM24TRIM33KDM4E | |
| SCHEMBL1389512 | 0.83 | ERN1 (0.48) | ERN1TRIM24TRIM33MEN1NPC1 | |
| SCHEMBL29955820 | 0.78 | ERN1 (0.39) | ERN1TYRTRIM24TRIM33KDM4E | |
| SCHEMBL899188 | 0.78 | TDP1 (0.45) | ERN1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL29411195 | 0.78 | TDP1 (0.45) | ERN1KDM4EMEN1NPC1RAB9A | |
| SCHEMBL13410344 | 0.78 | ERN1 (0.39) | ERN1TYRTRIM24TRIM33KDM4E | |
| SCHEMBL29952308 | 0.75 | ERN1 (0.35) | ERN1 | |
| SCHEMBL7186781 | 0.75 | ERN1 (0.43) | ERN1TYRTRIM24TRIM33 | |
| SCHEMBL29954366 | 0.75 | TDP1 (0.35) | ERN1 | |
| SCHEMBL15332623 | 0.75 | ERN1 (0.41) | ERN1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |