Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033844 | 1.00 | KLKB1 (0.36) | KLKB1METTL3ENPP2 | |
| SCHEMBL29174260 | 0.88 | METTL3 (0.35) | KLKB1METTL3 | |
| SCHEMBL29957817 | 0.88 | KLKB1 (0.38) | KLKB1METTL3 | |
| SCHEMBL27033780 | 0.88 | KLKB1 (0.38) | KLKB1METTL3 | |
| SCHEMBL27033979 | 0.88 | KLKB1 (0.36) | KLKB1METTL3 | |
| SCHEMBL29957930 | 0.88 | KLKB1 (0.36) | KLKB1METTL3 | |
| SCHEMBL29958373 | 0.88 | KLKB1 (0.35) | KLKB1METTL3 | |
| SCHEMBL27033856 | 0.88 | KLKB1 (0.35) | KLKB1METTL3 | |
| SCHEMBL29957564 | 0.85 | KLKB1 (0.37) | KLKB1METTL3 | |
| SCHEMBL27033353 | 0.85 | KLKB1 (0.37) | KLKB1METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308228-A1 | PLASMA KALLIKREIN INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| CN-117396474-A | Plasma kallikrein inhibitors | 武田药品工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022197756-A1 | PLASMA KALLIKREIN INHIBITORS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |