Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635493 | 1.00 | MAPT (0.43) | MAPTAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL23243620 | 0.87 | MAPT (0.43) | MAPTAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL29632664 | 0.87 | MAPT (0.43) | MAPTAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL31053255 | 0.84 | GAA (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7886929 | 0.84 | GAA (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5954084 | 0.83 | HPGD (0.42) | ALDH1A1MEN1KMT2AHSP90AB1KDM4E | |
| SCHEMBL7133160 | 0.83 | MAPT (0.49) | MAPTAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL19974304 | 0.83 | MTNR1A (0.50) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL31092358 | 0.83 | MTNR1A (0.50) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL13136740 | 0.82 | MAPT (0.42) | MAPTAKR1C3ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434417-A | Cyclic sulfonamide ribonucleotide reductase (RNR) inhibitors and uses thereof | 无界生物公司 | 2024-08-02 | — | — | CN | disclosed |
| EP-4308228-A1 | PLASMA KALLIKREIN INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022197756-A1 | PLASMA KALLIKREIN INHIBITORS | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2022-09-22 | — | — | WO | disclosed |