Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970241 | 0.90 | AGTR2 (0.41) | AGTR2LMNAL3MBTL1GRM2PIK3CA | |
| SCHEMBL23831146 | 0.88 | AGTR2 (0.49) | AGTR2KCNH2 | |
| SCHEMBL30195046 | 0.86 | AGTR2 (0.44) | AGTR2GRM2AGTR1CA12CA1 | |
| SCHEMBL23831166 | 0.85 | AGTR2 (0.49) | AGTR2KCNH2 | |
| SCHEMBL30194998 | 0.85 | AGTR2 (0.48) | AGTR2PIK3CA | |
| SCHEMBL23831155 | 0.85 | AGTR2 (0.52) | AGTR2AGTR1CA12CA1CA2 | |
| SCHEMBL29958671 | 0.83 | AGTR2 (0.58) | AGTR2AGTR1 | |
| SCHEMBL23121085 | 0.81 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL3528765 | 0.80 | AGTR2 (0.62) | AGTR2AGTR1 | |
| SCHEMBL30970242 | 0.79 | CYP2D6 (0.49) | AGTR2GRM2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313953-A1 | SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS | Vicore Pharma AB (SE) | 2024-02-07 | — | — | EP | disclosed |
| CN-117222624-A | Selective angiotensin II receptor ligands | 维科尔药物公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2022200785-A1 | SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS | VICORE PHARMA AB (SE) | 2022-09-29 | — | — | WO | disclosed |