Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Nicotinate SCHEMBL24853 | 1.00 | L3MBTL1 (0.71) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL1330922 | 1.00 | L3MBTL1 (0.71) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL8164637 | 1.00 | L3MBTL1 (0.71) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL29234036 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL9408506 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL27261943 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL8071110 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL11484012 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL30525807 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A | |
| Ethyl Nicotinate SCHEMBL27665006 | 0.98 | L3MBTL1 (0.69) | L3MBTL1LMNAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392414-A1 | INHIBITORS OF NLRP3 | PTC Therapeutics, Inc. (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028534-A1 | INHIBITORS OF NLRP3 | PTC THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022226161-A1 | GLUN2 SUBUNIT SELECTIVE ANTAGONISTS OF THE N-METHYL-D-ASPARTATE RECEPTORS | EMORY UNIVERSITY (US) | 2022-10-27 | — | — | WO | disclosed |