Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.62 |
| ▸ | FNTB | P49356 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581351 | 1.00 | FNTA (0.62) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL21835176 | 0.88 | FNTA (0.65) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL30522511 | 0.88 | FNTA (0.65) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL1312788 | 0.87 | C3AR1 (0.55) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL8607468 | 0.86 | FNTA (0.64) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL5718112 | 0.85 | ALDH1A1 (0.67) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL27655647 | 0.85 | FNTA (0.62) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL13621174 | 0.84 | FNTA (0.64) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL18389960 | 0.81 | HSD11B1 (0.69) | FNTAFNTBALDH1A1KDM4EMEN1 | |
| SCHEMBL22493291 | 0.81 | FNTA (0.58) | FNTAFNTBALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308122-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-01-24 | — | — | EP | disclosed |
| CN-116981459-A | Heterocyclic derivatives as janus kinase inhibitors | 奇斯药制品公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2022194779-A1 | HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2022-09-22 | — | — | WO | disclosed |