SCHEMBL29958892

SCHEMBL29958892

O=C(O)c1cccc(-c2cc(C(=O)O)ncc2C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDT P30046 1/20 1.00
AXL P30530 2/20 0.51
FOLH1 Q04609 2/20 0.49
KMO O15229 2/20 0.49
PLA2G2A P14555 1/20 0.48
PTPN11 Q06124 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
MAOA P21397 1/20 0.45
BLVRB P30043 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
KDM4E B2RXH2 1/20 0.45
KDM6B O15054 1/20 0.45
TET3 O43151 1/20 0.45
KDM4A O75164 1/20 0.45
BBOX1 O75936 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
KDM5A P29375 1/20 0.45
KDM5C P41229 1/20 0.45
ASPH Q12797 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806999 1.00 DDT (1.00) DDTAXLFOLH1KMOPLA2G2A
SCHEMBL686861 0.85 DDT (0.74) DDTKMOKDM4EALDH1A1ASPH
SCHEMBL29914342 0.85 DDT (0.74) DDTKMOKDM4EALDH1A1ASPH
SCHEMBL10782352 0.80 DDT (0.67) DDTFOLH1KMOPLA2G2APTPN11
SCHEMBL28557056 0.78 DDT (0.62) DDTKDM4EKDM6BTET3KDM4A
SCHEMBL2947834 0.77 KMO (0.63) DDTFOLH1KMOPLA2G2APTPN11
SCHEMBL29400093 0.77 KMO (0.63) DDTFOLH1KMOPLA2G2APTPN11
SCHEMBL31733899 0.77 DDT (0.62) DDTAXLFOLH1KMOALDH1A1
SCHEMBL29772925 0.76 DDT (0.61) DDTAXLKMOMAP4K4RXRA
SCHEMBL28563936 0.76 DDT (0.61) DDTAXLKMOMAP4K4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117185996-B Intermediate of 4-CPPC and preparation method thereof 烟台皓元生物医药科技有限公司 2026-03-20 CN disclosed
CN-117185996-B Intermediate of 4-CPPC and preparation method thereof 烟台皓元生物医药科技有限公司 2026-03-20 CN disclosed
CN-118028474-B Use of substance for removing nucleated red blood cells in spleen of patient in preparation of medicine for treating acute myelogenous leukemia 细胞生态海河实验室 2024-07-09 CN disclosed
CN-118028474-A Use of substance for removing nucleated red blood cells in spleen of patient in preparation of medicine for treating acute myelogenous leukemia 细胞生态海河实验室 2024-05-14 CN disclosed
US-20240139241-A1 COMPOSITIONS AND METHODS FOR CONDITIONING PATIENTS FOR CELL THERAPY CREATE MEDICINES, INC. 2024-05-02 US disclosed
EP-4326286-A2 COMPOSITIONS AND METHODS FOR CONDITIONING PATIENTS FOR CELL THERAPY Myeloid Therapeutics, Inc. (US) 2024-02-28 EP disclosed
WO-2024039683-A1 COMPOSITIONS AND METHODS FOR CONDITIONING PATIENTS FOR CELL THERAPY MYELOID THERAPEUTICS, INC. (US) 2024-02-22 WO disclosed
CN-117185996-A Intermediate of 4-CPPC and preparation method thereof 烟台皓元生物医药科技有限公司 2023-12-08 CN disclosed
CN-117185996-A Intermediate of 4-CPPC and preparation method thereof 烟台皓元生物医药科技有限公司 2023-12-08 CN disclosed
CN-117185996-A Intermediate of 4-CPPC and preparation method thereof 烟台皓元生物医药科技有限公司 2023-12-08 CN disclosed
WO-2023031246-A1 SUBSTITUTED THIOPHENE COMPOUNDS AS D-DOPACHROME TAUTOMERASE INHIBITORS RIJKSUNIVERSITEIT GRONINGEN (NL) 2023-03-09 WO disclosed
WO-2022226355-A2 COMPOSITIONS AND METHODS FOR CONDITIONING PATIENTS FOR CELL THERAPY MYELOID THERAPEUTICS, INC. (US) 2022-10-27 WO disclosed