Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880662 | 1.00 | MAPT (0.59) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL5563187 | 0.94 | MAPT (0.54) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL10127594 | 0.87 | MAPT (0.55) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL282776 | 0.86 | NR1H2 (0.49) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL29649928 | 0.86 | NR1H2 (0.49) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL78966 | 0.85 | ALDH1A1 (0.56) | MAPTKDM4ENR1H2TP53SMN1; SMN2 | |
| SCHEMBL16719192 | 0.84 | MAPT (0.53) | MAPTKDM4ERAD52NR1H2TP53 | |
| SCHEMBL25194643 | 0.83 | ALDH1A1 (0.59) | MAPTKDM4ENR1H2TP53SMN1; SMN2 | |
| SCHEMBL1929368 | 0.83 | ALDH1A1 (0.59) | MAPTKDM4ENR1H2TP53SMN1; SMN2 | |
| SCHEMBL30336413 | 0.83 | ALDH1A1 (0.59) | MAPTKDM4ENR1H2TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431239-A | Compounds, pharmaceutical compositions, kits and uses thereof | 密执安大学评议会 | 2025-02-14 | — | — | CN | disclosed |
| CN-119060018-A | N, N-diaryl urea derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-113710241-B | Substituted bicyclic and tetracyclic quinones and related methods of use | 密执安大学评议会 | 2024-11-15 | — | — | CN | disclosed |
| WO-2022226182-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-27 | — | — | WO | disclosed |