Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388614 | 1.00 | MAPT (0.47) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL23976335 | 0.91 | CLK1 (0.46) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL30107523 | 0.91 | CLK1 (0.46) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL152013 | 0.75 | CYP19A1 (0.45) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL16968057 | 0.75 | DYRK1A (0.52) | MAPTCLK1DYRK1APRKCZCYP19A1 | |
| SCHEMBL1018440 | 0.75 | CLK1 (0.46) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL239390 | 0.75 | CYP2A6 (0.54) | CYP2A6KDM4E | |
| SCHEMBL30502940 | 0.75 | CYP2A6 (0.54) | CYP2A6KDM4E | |
| SCHEMBL18459079 | 0.74 | MAPT (0.47) | MAPTCLK1DYRK1ACSNK1DCSNK1E | |
| SCHEMBL1098583 | 0.74 | PDPK1 (0.59) | MAPTCLK1DYRK1ACSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713096-A1 | CDK INHIBITOR COMPOUNDS | Aleksia Therapeutics, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| CN-115135642-B | Inhibitors of EGFR mutant forms | 缆图药品公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024238574-A1 | CDK INHIBITOR COMPOUNDS | ALEKSIA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| EP-4143178-A1 | CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS | Global Blood Therapeutics, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115135642-A | Inhibitors of mutant forms of EGFR | 缆图药品公司 | 2022-09-30 | — | — | CN | disclosed |