Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502940 | 1.00 | CYP2A6 (0.54) | CYP2A6CYP1A2PDPK1NPC1PLAU | |
| Bromide SCHEMBL11824489 | 0.98 | CYP2A6 (0.52) | CYP2A6CYP1A2PDPK1NPC1PLAU | |
| SCHEMBL20951048 | 0.78 | ALDH1A1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3875328 | 0.78 | NPC1 (0.39) | CYP2A6CYP1A2PDPK1NPC1RAB9A | |
| SCHEMBL23705771 | 0.78 | CLK4 (0.51) | CYP1A2NPC1RAB9A | |
| SCHEMBL32682142 | 0.78 | ESR1 (0.48) | NPC1RAB9A | |
| SCHEMBL10976089 | 0.76 | CYP2A6 (0.50) | CYP2A6NPC1HTR3A | |
| SCHEMBL3388614 | 0.75 | MAPT (0.47) | CYP2A6KDM4E | |
| SCHEMBL30107523 | 0.75 | CLK1 (0.46) | CYP2A6KDM4E | |
| SCHEMBL23976335 | 0.75 | CLK1 (0.46) | CYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865932-B | Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4727939-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | claimed |
| WO-2024259116-A1 | 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | claimed |
| CN-118634752-A | Diazotization continuous synthesis method of intermediate 3-hydroxy halogenated nitrogen-containing hybrid ring | 北京六合宁远医药科技股份有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-117865932-A | Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity | 北京化工大学 | 2024-04-12 | — | — | CN | claimed |
| CN-114409635-B | Compound and preparation method and application thereof | 五邑大学 | 2024-02-09 | — | — | CN | claimed |
| CN-113877483-B | Low-temperature continuous synthesis device and method for pharmaceutical intermediate halogenated isoquinoline boric acid | 烟台宁远药业有限公司 | 2023-11-24 | — | — | CN | claimed |
| US-20230138130-A1 | NOVEL COMPOUNDS FOR PREPARATION OF MICROTUBULE ASSOCIATED TAU PROTEIN IMAGING AGENTS, PREPARATION METHODS AND MEDICINAL USES THEREOF | INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) | 2023-05-04 | — | — | US | claimed |
| CN-114409635-A | Compound and preparation method and application thereof | 五邑大学 | 2022-04-29 | — | — | CN | claimed |
| CN-108658860-B | Preparation method of 3-chloro-5, 6,7, 8-tetrahydroisoquinoline | 成都睿智化学研究有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-108658860-A | A kind of preparation method of the chloro- 5,6,7,8- tetrahydroisoquinolines of 3- | 成都睿智化学研究有限公司 | 2018-10-16 | — | — | CN | claimed |
| CN-108178247-A | The graphite electrode modified based on CrO-FeO-PbO and quinoline | 光合强化（北京）生物科技有限公司 | 2018-06-19 | — | — | CN | claimed |
| CN-104629745-A | Organic electrophosphorescence material, preparation method and organic electroluminescent device thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-104628642-A | Organic iridium metal complex as well as preparation method and application thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-104629741-A | Organic electrophosphorescence material, as well as preparation method and organic electroluminescent device thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-104628777-A | Organic metal iridium complex, as well as preparation method and application thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-104629749-A | Organic electrophosphorescence material, as well as preparation method and organic electroluminescent device thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-104628782-A | Organic iridium metal complex as well as preparation method and application thereof | OCEANS KING LIGHTING SCIENCE | 2015-05-20 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |
| US-4795621-A | CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND | SHIN NISSO KAKO CO., LTD. (JP) | 1989-01-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138130-A1 | NOVEL COMPOUNDS FOR PREPARATION OF MICROTUBULE ASSOCIATED TAU PROTEIN IMAGING AGENTS, PREPARATION METHODS AND MEDICINAL USES THEREOF | MAPT, MAP1B, MAP2 | CYP2A6 4847/4885CYP1A2 4532/4885PDPK1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.