Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | USP2 | O75604 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | IDO1 | P14902 | 2/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.77 |
| ▸ | HAT1 | O14929 | 4/20 | 0.58 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TST | Q16762 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335748 | 1.00 | MEN1 (0.77) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL13966082 | 0.88 | MEN1 (0.66) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL29603980 | 0.87 | MEN1 (1.00) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL16476451 | 0.86 | MEN1 (0.71) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL14335564 | 0.86 | MEN1 (0.74) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL29959870 | 0.86 | MEN1 (0.71) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL20906884 | 0.86 | MEN1 (0.71) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL15705631 | 0.85 | MEN1 (0.70) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL864193 | 0.85 | MEN1 (0.69) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL11304043 | 0.85 | MEN1 (0.73) | MEN1KMT2AKDM4EUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492104-B1 | USE OF 10H-BENZO [G] PTERIDIN-2,4-DION DERIVATIVES | TRIOPTOTEC GMBH (DE) | 2023-02-15 | — | — | EP | disclosed |
| EP-3586632-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE OF SAME | TRIOPTOTEC GMBH (DE) | 2022-09-28 | — | — | EP | disclosed |