Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | USP2 | O75604 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.71 |
| ▸ | IDO1 | P14902 | 1/20 | 0.71 |
| ▸ | HAT1 | O14929 | 4/20 | 0.56 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.56 |
| ▸ | KAT7 | O95251 | 1/20 | 0.56 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | CASP7 | P55210 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29959870 | 1.00 | MEN1 (0.71) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL14335564 | 0.89 | MEN1 (0.74) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL15705631 | 0.88 | MEN1 (0.70) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL19415773 | 0.87 | MEN1 (0.66) | MEN1KMT2AKDM4EUSP2MAPT | |
| Hydrochloric Acid SCHEMBL15665822 | 0.87 | MEN1 (0.69) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL14335748 | 0.86 | MEN1 (0.77) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL29959592 | 0.86 | MEN1 (0.77) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL16476441 | 0.85 | MEN1 (0.66) | MEN1KMT2AKDM4EUSP2MAPT | |
| SCHEMBL864786 | 0.84 | MEN1 (0.71) | MEN1KMT2AKDM4EUSP2MAPT | |
| Bromide SCHEMBL17254515 | 0.84 | MEN1 (0.65) | MEN1KMT2AKDM4EUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586632-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR PRODUCING SAME AND USE OF SAME | TRIOPTOTEC GMBH (DE) | 2022-09-28 | — | — | EP | disclosed |
| EP-2723743-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |
| US-9185913-B2 | 10H-benzo[g]pteridine-2,4-dione derivatives, method for the production thereof, and use thereof | TRIOPTOTEC GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-9185913-B2 | 10H-benzo[g]pteridine-2,4-dione derivatives, method for the production thereof, and use thereof | TRIOPTOTEC GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2014-07-17 | — | — | US | disclosed |
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | DHPS, DOHH, DPYD | MEN1 2099/4885KMT2A 1148/4885KDM4E 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.