Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536954 | 0.90 | KMT2A (0.47) | KMT2AMEN1SMN1; SMN2BCHEMAPT | |
| SCHEMBL1916468 | 0.88 | SMN1; SMN2 (0.58) | KMT2AMEN1SMN1; SMN2BCHEMAPT | |
| SCHEMBL1826469 | 0.85 | ADRB3 (0.42) | KMT2AMEN1SMN1; SMN2BCHEMAPT | |
| SCHEMBL7864108 | 0.83 | BCHE (0.54) | KMT2AMEN1BCHECYP2C19ANPEP | |
| SCHEMBL1823827 | 0.83 | ALDH1A1 (0.42) | KMT2AMEN1SMN1; SMN2BCHEMAPT | |
| SCHEMBL1627443 | 0.82 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2BCHEMAPT | |
| SCHEMBL1826338 | 0.82 | BCHE (0.44) | KMT2AMEN1BCHE | |
| SCHEMBL4855629 | 0.82 | SLC16A3 (0.45) | KMT2AMEN1 | |
| SCHEMBL4855616 | 0.81 | CASR (0.47) | KMT2AMEN1BCHE | |
| SCHEMBL23102214 | 0.81 | MAPT (0.55) | KMT2AMEN1SMN1; SMN2BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |