Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23070086 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL23070302 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL29959878 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL448500 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL23070050 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL23070051 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL29960050 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HTTKMT2AMEN1NPC1 | |
| SCHEMBL451476 | 0.84 | ALDH1A1 (0.49) | ALDH1A1RAB9A | |
| SCHEMBL1553206 | 0.83 | PDE10A (0.54) | NPC1 | |
| SCHEMBL23070254 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | UT RESEARCH FOUNDATION | 2022-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | NEFM, EIF2AK2, PMP22 | ALDH1A1 1861/4885HTT 4173/4885KMT2A 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.