Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23070048 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL23069883 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL29959752 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL23069833 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL23069834 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL29960052 | 0.93 | ALDH1A1 (0.45) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL15798534 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HTTKDRMAPTLMNA | |
| SCHEMBL29960005 | 0.84 | NPC1 (0.46) | ALDH1A1HTTMAPTLMNANPC1 | |
| SCHEMBL23069855 | 0.84 | NPC1 (0.46) | ALDH1A1HTTMAPTLMNANPC1 | |
| SCHEMBL23069888 | 0.84 | NPC1 (0.48) | ALDH1A1MAPTLMNANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | UT RESEARCH FOUNDATION | 2022-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | NEFM, EIF2AK2, PMP22 | ALDH1A1 1861/4885HTT 4173/4885KDR 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.