Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 20/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960006 | 0.77 | FEN1 (0.62) | FEN1ERCC1ERCC4ERCC5CA12 | |
| SCHEMBL29959996 | 0.76 | FEN1 (0.67) | FEN1 | |
| SCHEMBL29960340 | 0.75 | FEN1 (1.00) | FEN1ERCC1ERCC4ERCC5CA12 | |
| SCHEMBL18670294 | 0.74 | FEN1 (1.00) | FEN1ERCC1ERCC4ERCC5CA12 | |
| SCHEMBL31485136 | 0.74 | PBRM1 (0.58) | — | |
| SCHEMBL3910030 | 0.74 | PBRM1 (0.58) | — | |
| SCHEMBL18670508 | 0.72 | FEN1 (1.00) | FEN1ERCC1ERCC4ERCC5CA12 | |
| SCHEMBL29959783 | 0.71 | FEN1 (0.63) | FEN1ERCC1ERCC4ERCC5CA12 | |
| SCHEMBL717723 | 0.70 | AKR1C3 (0.64) | — | |
| SCHEMBL13752239 | 0.70 | PIK3CG (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430978-B | 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators | 路德维格癌症研究所有限责任公司 | 2022-11-22 | — | — | CN | disclosed |