Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 9/20 | 0.63 |
| ▸ | ERCC1 | P07992 | 4/20 | 0.59 |
| ▸ | ERCC4 | Q92889 | 4/20 | 0.59 |
| ▸ | DNASE1 | P24855 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 8/20 | 0.58 |
| ▸ | CA9 | Q16790 | 8/20 | 0.58 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.58 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29152717 | 0.80 | ATM (0.57) | MEN1ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL29959916 | 0.78 | FEN1 (1.00) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL29959939 | 0.78 | FEN1 (0.69) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL29933774 | 0.74 | FEN1 (1.00) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL1520708 | 0.74 | FEN1 (1.00) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL24262310 | 0.74 | FEN1 (0.63) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL18670563 | 0.74 | FEN1 (1.00) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL9760930 | 0.73 | ADORA3 (0.56) | CA12CA9ALDH1A1LMNAGLA | |
| SCHEMBL29960069 | 0.72 | FEN1 (0.61) | FEN1ERCC1ERCC4DNASE1CA12 | |
| SCHEMBL18670385 | 0.72 | FEN1 (1.00) | FEN1ERCC1ERCC4DNASE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430978-B | 3-hydroxy-quinazoline-2, 4-dione derivatives and their use as nuclease modulators | 路德维格癌症研究所有限责任公司 | 2022-11-22 | — | — | CN | disclosed |