Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960700 | 0.91 | ESR2 (0.44) | ESR2NR1H2PRMT5WDR77MAPK1 | |
| SCHEMBL29960191 | 0.81 | ESR2 (0.43) | ESR2NR1H2PRMT5WDR77MAPK1 | |
| SCHEMBL16353768 | 0.77 | ESR2 (0.43) | ESR2NR1H2PRMT5WDR77MAPK1 | |
| SCHEMBL29960861 | 0.77 | NAMPT (0.35) | ESR2PRMT5WDR77MAPK1USP30 | |
| SCHEMBL29960661 | 0.77 | ESR2 (0.43) | ESR2NR1H2PRMT5WDR77USP30 | |
| SCHEMBL29960214 | 0.77 | ESR2 (0.43) | ESR2NR1H2PRMT5WDR77USP30 | |
| SCHEMBL29960457 | 0.77 | ESR2 (0.43) | ESR2NR1H2PRMT5WDR77USP30 | |
| SCHEMBL29960635 | 0.77 | ESR2 (0.46) | ESR2NR1H2 | |
| SCHEMBL16444682 | 0.75 | ESR2 (0.44) | ESR2NR1H2PRMT5WDR77MAPK1 | |
| SCHEMBL16353611 | 0.75 | ESR2 (0.44) | ESR2NR1H2PRMT5WDR77MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |