Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960579 | 0.96 | ESR2 (0.43) | ESR2NR1H2STSMEN1KMT2A | |
| SCHEMBL29960457 | 0.87 | ESR2 (0.43) | ESR2NR1H2USP2SMN1; SMN2NPC1 | |
| SCHEMBL29960661 | 0.87 | ESR2 (0.43) | ESR2NR1H2USP2SMN1; SMN2NPC1 | |
| SCHEMBL29960214 | 0.87 | ESR2 (0.43) | ESR2NR1H2MEN1KMT2AEPHA2 | |
| SCHEMBL29960704 | 0.86 | PDE4B (0.44) | ESR2NR1H2STSMEN1KMT2A | |
| SCHEMBL29960700 | 0.83 | ESR2 (0.44) | ESR2NR1H2USP2SMN1; SMN2 | |
| SCHEMBL29960308 | 0.81 | USP30 (0.43) | ESR2NR1H2USP2SMN1; SMN2NPC1 | |
| SCHEMBL29960271 | 0.77 | ESR2 (0.44) | ESR2NR1H2 | |
| SCHEMBL16353790 | 0.76 | ESR2 (0.47) | ESR2NR1H2STSMEN1KMT2A | |
| SCHEMBL29960522 | 0.76 | ESR2 (0.42) | ESR2NR1H2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |