Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960699 | 1.00 | MAPT (0.42) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL1680515 | 0.78 | METAP1 (0.46) | MAPTLMNACA12CA1CA2 | |
| SCHEMBL31021844 | 0.77 | CYP2C9 (0.48) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL15640149 | 0.76 | MAPK8 (0.58) | MAPTLMNAHTTPKMALDH1A1 | |
| SCHEMBL7748042 | 0.75 | CA12 (0.57) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL7748046 | 0.75 | CA12 (0.57) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL12660459 | 0.75 | CA12 (0.51) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL4727622 | 0.75 | METAP1 (0.44) | LMNACA12CA1CA2CA9 | |
| SCHEMBL13931555 | 0.74 | TTR (0.36) | MAPTLMNAHTTTTRDPP4 | |
| SCHEMBL1533931 | 0.74 | TTR (0.50) | MAPTTTRDPP4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |