Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29959875 | 0.98 | IDO1 (0.50) | IDO1GSK3BTDO2EGFRSRC | |
| SCHEMBL29960605 | 0.81 | IDO1 (0.41) | IDO1GSK3BTDO2EGFRHTR2A | |
| Hydrochloric Acid SCHEMBL29960558 | 0.80 | IDO1 (0.40) | IDO1GSK3BTDO2EGFRHTR2A | |
| SCHEMBL29959995 | 0.77 | KMT2A (0.40) | IDO1GSK3BTDO2EGFRSRC | |
| SCHEMBL1542794 | 0.76 | IDO1 (0.77) | IDO1GSK3BTDO2EGFRSRC | |
| Hydrochloric Acid SCHEMBL7419440 | 0.74 | IDO1 (0.74) | IDO1GSK3BTDO2EGFRSRC | |
| SCHEMBL24692070 | 0.72 | HTR5A (0.58) | IDO1TSHRHTR5A | |
| SCHEMBL22972507 | 0.72 | IDO1 (0.43) | IDO1GSK3BTDO2EGFRHSD17B10 | |
| SCHEMBL29713182 | 0.72 | HTR5A (0.58) | IDO1TSHRHTR5A | |
| SCHEMBL28870083 | 0.72 | HSD17B10 (0.67) | HTR2AHSD17B10KDM4ETNKS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |