SCHEMBL29960673

SCHEMBL29960673

O=C1NCC2CCOc3cccc1c32

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 12/20 0.41
MAP3K14 Q99558 1/20 0.40
PIM1 P11309 4/20 0.34
PIM3 Q86V86 4/20 0.34
PIM2 Q9P1W9 4/20 0.34
FABP6 P51161 1/20 0.34
PARP3 Q9Y6F1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29960879 0.84 PARP1 (0.43) PARP1PIM1PIM3PIM2PARP3
SCHEMBL29959964 0.75 MAP3K14 (0.41) MAP3K14
SCHEMBL3594200 0.75 MAP3K14 (0.41) MAP3K14
SCHEMBL31037184 0.71 PARP1 (0.56) PARP1
SCHEMBL6854090 0.71 PARP1 (0.56) PARP1
Hydrochloric Acid SCHEMBL2456613 0.70 PARP1 (0.55) PARP1
SCHEMBL22248076 0.69 PARP1 (0.46) PARP1PIM1PARP3
SCHEMBL5138055 0.69 PARP1 (0.43) PARP1
SCHEMBL29960815 0.69 MAP3K14 (0.39) MAP3K14
Hydrochloric Acid SCHEMBL29960209 0.68 MAP3K14 (0.41) MAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204150-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS BLUE OAK PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed