Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249765 | 0.89 | TSHR (0.44) | IDO1TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL26915622 | 0.86 | IGF1R (0.34) | IDO1TSHRDAOCNR1CA2 | |
| SCHEMBL24197605 | 0.84 | TDP1 (0.42) | IDO1TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL2278502 | 0.84 | TDP1 (0.42) | IDO1TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL2732843 | 0.82 | ACHE (0.39) | IDO1TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL27798832 | 0.80 | IDO1 (0.37) | IDO1TSHRTDP1DAOCNR1 | |
| SCHEMBL1247139 | 0.78 | TDP1 (0.34) | IDO1TDP1KDM4EALDH1A1ALOX5 | |
| SCHEMBL15516951 | 0.78 | IDO1 (0.35) | IDO1TSHRDAOCNR1 | |
| SCHEMBL27830320 | 0.78 | TDP1 (0.34) | IDO1TDP1KDM4EALDH1A1ALOX5 | |
| SCHEMBL31337562 | 0.76 | TDP1 (0.36) | IDO1TDP1KDM4EALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |