Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29960692 | 0.85 | ALDH1A1 (0.39) | SSTR4CYP2D6POLBALDH1A1MAPT | |
| SCHEMBL22035765 | 0.77 | SSTR4 (0.38) | SSTR4ALDH1A1TSHRABCB1 | |
| SCHEMBL26756258 | 0.77 | SSTR4 (0.38) | SSTR4ALDH1A1TSHRABCB1 | |
| SCHEMBL23934537 | 0.75 | TSHR (0.36) | SSTR4POLBALDH1A1MAPTCYP3A4 | |
| SCHEMBL27020293 | 0.73 | GAA (0.40) | CYP2D6ALDH1A1CYP2C19TSHRKDM4E | |
| SCHEMBL24593692 | 0.70 | SSTR4 (0.42) | SSTR4MAPK1KMT2A | |
| SCHEMBL22143902 | 0.70 | SSTR4 (0.42) | SSTR4MAPK1KMT2A | |
| SCHEMBL24593501 | 0.70 | SSTR4 (0.42) | SSTR4MAPK1KMT2A | |
| SCHEMBL22143707 | 0.70 | SSTR4 (0.42) | SSTR4MAPK1KMT2A | |
| SCHEMBL22125742 | 0.70 | SSTR4 (0.42) | SSTR4MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204150-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |