SCHEMBL2996130

SCHEMBL2996130

CCC(C)(CC(C)(CC)C1CCCCC1)C1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
SHBG P04278 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28157000 0.90 CYP1A2 (0.39) CYP1A2SHBGMEN1ALDH1A1LMNA
SCHEMBL2994171 0.81 CYP1A2 (0.38) CYP1A2SHBG
SCHEMBL2985857 0.79 CYP1A2 (0.41) CYP1A2
SCHEMBL14451896 0.79 MEN1 (0.33) MEN1ALDH1A1LMNAALOX12KMT2A
SCHEMBL28046495 0.78 MEN1 (0.36) CYP1A2MEN1ALDH1A1LMNAALOX12
SCHEMBL20671574 0.78 SIGMAR1 (0.34) CYP1A2MEN1ALDH1A1LMNAALOX12
SCHEMBL20031048 0.78 SIGMAR1 (0.34) CYP1A2MEN1ALDH1A1LMNAALOX12
SCHEMBL3001150 0.78 CYP1A2 (0.45) CYP1A2
SCHEMBL14451912 0.78
SCHEMBL3002888 0.75 MEN1 (0.37) CYP1A2MEN1ALDH1A1LMNAALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed