Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21315681 | 1.00 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL21315647 | 0.98 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL21315683 | 0.96 | MTNR1A (0.53) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL21315645 | 0.95 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21315660 | 0.82 | MAPT (0.52) | MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL21315658 | 0.81 | MTNR1A (0.58) | MTNR1AMTNR1B | |
| SCHEMBL21315673 | 0.80 | MAPT (0.53) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL29961819 | 0.80 | MAPT (0.53) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL21315684 | 0.79 | MAPT (0.54) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E | |
| SCHEMBL29961789 | 0.79 | MAPT (0.54) | MTNR1AMTNR1BNQO2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181108-A | Compound and preparation method, pharmaceutical composition and application thereof | 艾奇实验室制药有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110088092-B | Compounds, processes for their preparation, pharmaceutical compositions, uses of compounds and methods for treating psychiatric and/or sleep disorders | 艾奇实验室制药有限公司 | 2022-10-04 | — | — | CN | disclosed |