Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CEL | P19835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832498 | 0.96 | CYP1A2 (0.43) | SIGMAR1CYP1A2CYP2D6EPHX1OPRK1 | |
| SCHEMBL10748317 | 0.88 | CYP1A2 (0.38) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL30342933 | 0.80 | CYP1A2 (0.42) | SIGMAR1CYP1A2CYP2D6EPHX1 | |
| SCHEMBL29336691 | 0.80 | SIGMAR1 (0.50) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL24311127 | 0.78 | SIGMAR1 (0.53) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL11000961 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2D6EPHX1 | |
| SCHEMBL21958288 | 0.78 | SIGMAR1 (0.48) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL29995615 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2D6EPHX1 | |
| SCHEMBL11133777 | 0.78 | CYP1A2 (0.41) | CYP1A2CYP2D6EPHX1 | |
| SCHEMBL2688034 | 0.78 | CYP1A2 (0.45) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |
| US-4521324-A | Fluid for traction drive | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1985-06-04 | — | — | US | disclosed |