Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC2R | Q01718 | 19/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24918828 | 1.00 | MC2R (0.83) | MC2RMEN1NPC1MAPTKMT2A | |
| Formic Acid SCHEMBL29963568 | 0.97 | MC2R (0.79) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL29963567 | 0.93 | MC2R (0.72) | MC2R | |
| SCHEMBL29963050 | 0.93 | MC2R (0.73) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL29963678 | 0.91 | MC2R (0.69) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL21700598 | 0.91 | MC2R (1.00) | MC2R | |
| SCHEMBL21725661 | 0.91 | MC2R (1.00) | MC2R | |
| SCHEMBL21700652 | 0.90 | MC2R (0.78) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL21700844 | 0.89 | MC2R (0.81) | MC2RMEN1NPC1MAPTKMT2A | |
| SCHEMBL29963537 | 0.88 | MC2R (0.64) | MC2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054583-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-09-14 | — | — | EP | claimed |
| EP-4054583-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |