Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21309666 | 0.82 | HTR1D (0.37) | FABP7PIK3CDPIK3CABRD4MAPK14 | |
| SCHEMBL30072245 | 0.76 | FABP7 (0.45) | FABP7PIK3CDPIK3CAMAPK14PIK3CB | |
| SCHEMBL1570328 | 0.76 | FABP7 (0.45) | FABP7PIK3CDPIK3CAMAPK14PIK3CB | |
| SCHEMBL4175163 | 0.76 | ACMSD (0.43) | PRKDCTRIM24TRIM33BRD4CA12 | |
| SCHEMBL932928 | 0.76 | PIK3CD (0.45) | FABP7PIK3CDPIK3CAMAPK14PIK3CB | |
| SCHEMBL18857842 | 0.75 | MAPK14 (0.47) | FABP7PIK3CDPIK3CAMAPK14PIK3CB | |
| SCHEMBL31705648 | 0.74 | FABP7 (0.53) | FABP7PIK3CDPIK3CAPRKDCALDH1A1 | |
| SCHEMBL3107969 | 0.74 | FABP7 (0.53) | FABP7PIK3CDPIK3CAPRKDCALDH1A1 | |
| SCHEMBL24680921 | 0.73 | HTR1D (0.38) | FABP7PIK3CDPIK3CABRD4MAPK14 | |
| SCHEMBL22832713 | 0.73 | MAPK14 (0.50) | FABP7MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226668-A1 | HALO-SUBSTITUTED AMINO PYRIDINE COMPOUNDS AS INHIBITORS OF THE HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-11-03 | — | — | WO | disclosed |