Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965291 | 1.00 | TSHR (0.51) | TSHRCYP3A4SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL29965066 | 0.87 | SMN1; SMN2 (0.54) | TSHRCYP3A4SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL23199839 | 0.84 | SMN1; SMN2 (0.52) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL23199827 | 0.83 | SMN1; SMN2 (0.51) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL29965398 | 0.83 | CYP3A4 (0.46) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| Trifluoroacetic Acid SCHEMBL31198241 | 0.79 | CYP3A4 (0.46) | TSHRCYP3A4SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL30628897 | 0.79 | SMN1; SMN2 (0.50) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL12467310 | 0.79 | SMN1; SMN2 (0.50) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL30628898 | 0.79 | SMN1; SMN2 (0.50) | TSHRCYP3A4SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL30489099 | 0.76 | GAA (0.47) | TSHRCYP3A4SMN1; SMN2TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151260-A | Fulvestrant prodrugs | 卡希夫生物科学有限公司 | 2022-10-04 | — | — | CN | disclosed |