Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965675 | 0.87 | MAPT (0.46) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL23727122 | 0.80 | MAPT (0.47) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13398533 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL28976959 | 0.71 | ALDH1A1 (0.58) | MAPTALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL587189 | 0.70 | MAPT (0.34) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL581103 | 0.69 | GAA (0.35) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23467070 | 0.69 | MAPT (0.50) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8871550 | 0.69 | KDM4E (0.54) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23467066 | 0.69 | MAPT (0.50) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9367156 | 0.68 | ALDH1A1 (0.38) | ALDH1A1CYP2C19MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204109-A1 | QUINUCLIDINONE ANALOGUES AS ANTICANCER AGENTS | NEWAVE PHARMACEUTICAL INC. (US) | 2022-09-29 | — | — | WO | disclosed |