SCHEMBL29965302

SCHEMBL29965302

c1ccc2c(c1)-c1ccccc1C21c2ccccc2C2(c3ccccc3-c3ccccc32)c2cc3c(cc21)c1ccccc1n3-c1ccc(-n2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DUSP3 P51452 1/20 0.33
PTPN1 P18031 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HDAC4 P56524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20199460 1.00 KDM4E (0.46) KDM4EATML3MBTL1DUSP3PTPN1
SCHEMBL20199484 0.98 KDM4E (0.47) KDM4EATML3MBTL1DUSP3PTPN1
SCHEMBL20199437 0.95 L3MBTL1 (0.53) KDM4EATML3MBTL1DUSP3PTPN1
SCHEMBL20199461 0.94 L3MBTL1 (0.55) KDM4EATML3MBTL1DUSP3PTPN1
SCHEMBL20199793 0.93 KDM4E (0.47) KDM4EATML3MBTL1PTPN1KMT2A
SCHEMBL20199440 0.93 L3MBTL1 (0.44) KDM4EATML3MBTL1PTPN1MEN1
SCHEMBL20199452 0.93 KDM4E (0.47) KDM4EATML3MBTL1PTPN1KMT2A
SCHEMBL20199443 0.93 KDM4E (0.40) KDM4EATML3MBTL1LMNAMAPT
SCHEMBL20199593 0.93 KDM4E (0.44) KDM4EATML3MBTL1DUSP3PTPN1
SCHEMBL20199514 0.93 KDM4E (0.44) KDM4EATML3MBTL1DUSP3PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790119-B Organic compound, application thereof, organic mixture and organic electronic device 广州华睿光电材料有限公司 2022-11-04 CN disclosed