Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23671341 | 1.00 | KMT2A (0.43) | KMT2AHPGDSLRRK2CCR5RAB9A | |
| SCHEMBL23671342 | 1.00 | KMT2A (0.43) | KMT2AHPGDSLRRK2CCR5RAB9A | |
| SCHEMBL30611152 | 0.89 | KDM1A (0.44) | KMT2AHPGDSRAB9ADRD3GSK3A | |
| SCHEMBL29965837 | 0.89 | KDM1A (0.44) | KMT2AHPGDSRAB9ADRD3GSK3A | |
| SCHEMBL23671267 | 0.89 | KDM1A (0.44) | KMT2AHPGDSRAB9ADRD3GSK3A | |
| SCHEMBL23671266 | 0.89 | KDM1A (0.44) | KMT2AHPGDSRAB9ADRD3GSK3A | |
| SCHEMBL29965819 | 0.81 | THRB (0.49) | HPGDS | |
| SCHEMBL23671446 | 0.81 | THRB (0.49) | HPGDS | |
| SCHEMBL23671448 | 0.81 | THRB (0.49) | HPGDS | |
| SCHEMBL23663381 | 0.80 | THRB (0.42) | KMT2AHPGDSRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244037-B | Substituted triazinones as thyroid hormone receptor agonists | 诚益生物(美国)公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-4090652-A1 | SUBSTITUTED TRIAZINONES AS THYROID HORMONE RECEPTOR AGONISTS | Eccogene (Shanghai) Co., Ltd. (CN) | 2022-11-23 | — | — | EP | disclosed |
| CN-115244037-A | Substituted triazinones as thyroid hormone receptor agonists | 上海诚益生物科技有限公司 | 2022-10-25 | — | — | CN | disclosed |