Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.58 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018954 | 1.00 | KDR (0.62) | KDRKDM4EJAK3RAB9ANPC1 | |
| SCHEMBL13134396 | 0.89 | RAB9A (0.60) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27617535 | 0.83 | KDR (0.68) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL879570 | 0.82 | KDM4E (0.62) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4936483 | 0.82 | HDAC1 (0.64) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27866684 | 0.82 | NPC1 (0.80) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL651159 | 0.81 | KDR (0.74) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6029346 | 0.81 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL13991500 | 0.80 | KDR (0.60) | KDRKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16101601 | 0.80 | KDR (0.60) | KDRKDM4ERAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263760-A | Method for synthesizing tetrahydrobenzene-1-formamide compound by photocatalysis | 西南医科大学 | 2023-12-22 | — | — | CN | disclosed |
| CN-115260195-B | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-115260195-A | EGFR degradation agent | 上海齐鲁制药研究中心有限公司 | 2022-11-01 | — | — | CN | disclosed |