Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GPR183 | P32249 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632539 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL28642144 | 0.90 | KDM4E (0.69) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL28651380 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL29966876 | 0.88 | KDM4E (0.63) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL28651379 | 0.85 | ALDH1A1 (0.63) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL29966676 | 0.84 | ALDH1A1 (0.62) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL28635247 | 0.84 | ALDH1A1 (0.62) | KDM4EALDH1A1GPR183APPMEN1 | |
| SCHEMBL28632925 | 0.82 | ALDH1A1 (0.66) | KDM4EALDH1A1GPR183MEN1KMT2A | |
| SCHEMBL31533014 | 0.82 | GPR183 (0.66) | KDM4EALDH1A1GPR183ACHE | |
| SCHEMBL29966961 | 0.80 | APP (0.64) | KDM4EALDH1A1APPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461639-B | Piperazine-containing ferulic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | disclosed |