Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22547812 | 0.70 | GFER (0.58) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL29031856 | 0.69 | PARP1 (1.00) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL28959745 | 0.69 | GFER (0.46) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL26246971 | 0.68 | GFER (0.59) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL31014293 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL29031892 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL28353399 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL29031858 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL30472341 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 | |
| SCHEMBL30472346 | 0.68 | PARP1 (0.96) | PARP1GFERMAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368362-A | Quinoxalinone derivatives as BTK inhibitors and application thereof | 华东理工大学 | 2022-11-22 | — | — | CN | disclosed |