Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.47 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19434218 | 1.00 | GPR119 (0.47) | GPR119F2RL3CYP2C9 | |
| SCHEMBL29966725 | 1.00 | GPR119 (0.47) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19434302 | 1.00 | GPR119 (0.47) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19434166 | 0.93 | GPR119 (0.55) | GPR119F2RL3CYP2C9 | |
| SCHEMBL29966702 | 0.93 | GPR119 (0.55) | GPR119F2RL3CYP2C9 | |
| SCHEMBL29966755 | 0.93 | GPR119 (0.55) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19434170 | 0.93 | GPR119 (0.55) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19438327 | 0.91 | GPR119 (0.45) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19434260 | 0.91 | GPR119 (0.52) | GPR119F2RL3CYP2C9 | |
| SCHEMBL19434291 | 0.91 | GPR119 (0.52) | GPR119F2RL3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440078-B1 | HETEROCYCLIC GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD (IN) | 2022-09-28 | — | — | EP | claimed |