Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259028 | 1.00 | MAPT (0.52) | MAPTALDH1A1HSD17B10PSMB8CYP3A4 | |
| SCHEMBL5111018 | 0.75 | MAPT (0.48) | MAPTALDH1A1HSD17B10PSMB8CYP3A4 | |
| SCHEMBL360425 | 0.74 | PARP1 (0.55) | KDM4EAURKAPARP1 | |
| SCHEMBL340944 | 0.74 | PRKD3 (0.49) | KDM4ESYKAURKAPARP1 | |
| SCHEMBL29480586 | 0.74 | PRKD3 (0.49) | KDM4ESYKAURKAPARP1 | |
| SCHEMBL5389075 | 0.73 | ERAP1 (0.46) | MAPTALDH1A1HSD17B10PSMB8CYP3A4 | |
| Hydrochloric Acid SCHEMBL30775701 | 0.72 | PRKD3 (0.47) | KDM4ESYKAURKAPARP1 | |
| Hydrochloric Acid SCHEMBL30594385 | 0.72 | PRKD3 (0.47) | KDM4ESYKAURKAPARP1 | |
| 2-Mercaptobenzimidazole SCHEMBL29360590 | 0.70 | ALDH1A1 (1.00) | MAPTALDH1A1HSD17B10PSMB8CYP3A4 | |
| 2-Mercaptobenzimidazole SCHEMBL705730 | 0.70 | ALDH1A1 (1.00) | MAPTALDH1A1HSD17B10PSMB8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118059093-A | Inhibitors of short chain dehydrogenase activity for the treatment of fibrosis | 卡斯西部储备大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-115260164-B | Preparation method, structural composition and application of novel 4 (3H) -quinazolinone analogue in antitumor drugs | 杭州星鳌生物科技有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115260164-A | Preparation method and structural composition of novel 4 (3H) -quinazolinone analogue and application of analogue in antitumor drugs | 杭州星鳌生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |