Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19195067 | 1.00 | DGAT1 (0.50) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL21464703 | 0.86 | PRMT5 (0.46) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL16947773 | 0.84 | DGAT1 (0.50) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL860377 | 0.83 | DGAT1 (0.53) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL18530350 | 0.83 | DGAT1 (0.60) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL30117289 | 0.82 | PRMT5 (0.56) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL16947772 | 0.82 | PRMT5 (0.56) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL24811141 | 0.82 | USP30 (0.56) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL29891611 | 0.80 | STK17B (0.48) | DGAT1PRMT5WDR77AAK1USP30 | |
| SCHEMBL24814016 | 0.79 | USP30 (0.54) | DGAT1PRMT5WDR77AAK1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061800-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2022-09-28 | — | — | EP | disclosed |