Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.51 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394178 | 1.00 | HTR6 (0.51) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL23252295 | 0.91 | HTR6 (0.46) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL21636425 | 0.86 | HTR6 (0.41) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL21636626 | 0.85 | HTR6 (0.36) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL21636885 | 0.84 | HTR6 (0.38) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL21636412 | 0.84 | HTR6 (0.49) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL4601850 | 0.84 | HTR6 (0.54) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL21636628 | 0.82 | HTR6 (0.56) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL30132983 | 0.82 | HTR6 (0.44) | HTR6JAK2BTKCA1CA2 | |
| SCHEMBL23658787 | 0.82 | HTR6 (0.44) | HTR6JAK2BTKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090661-A1 | QUINOXALINE DERIVATIVES AS MODULATORS OF THE GLUCOCORTICOID RECEPTOR | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |