Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.56 |
| ▸ | FLT3 | P36888 | 6/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871292 | 1.00 | KDR (0.56) | KDRFLT3LCKCSF1RPLK4 | |
| SCHEMBL29967807 | 0.79 | KDR (0.50) | KDRFLT3LCKCSF1RAKT1 | |
| SCHEMBL29968393 | 0.75 | KDR (0.45) | KDRFLT3SCN5ASCN9AGAA | |
| SCHEMBL28871294 | 0.75 | KDR (0.45) | KDRFLT3SCN5ASCN9AGAA | |
| SCHEMBL419499 | 0.73 | KDR (0.56) | KDRFLT3LCKCSF1RSCN5A | |
| SCHEMBL20481783 | 0.71 | PDGFRA (0.52) | KDRFLT3JAK2CDK2SCN5A | |
| SCHEMBL17045395 | 0.69 | SCN9A (0.46) | KDRFLT3SCN5ASCN9AMEN1 | |
| SCHEMBL422378 | 0.69 | KDR (0.56) | KDRFLT3LCKCSF1RPLK4 | |
| SCHEMBL29794328 | 0.68 | MAPT (0.61) | MEN1GALR3GAAMAPTNPY1R | |
| SCHEMBL11120339 | 0.65 | EIF2AK2 (0.62) | KDRFLT3LCKCSF1RPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |