Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919617 | 1.00 | BTK (0.52) | BTKALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL27177141 | 1.00 | BTK (0.52) | BTKALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30919768 | 0.90 | BTK (0.50) | BTKSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL27262933 | 0.90 | BTK (0.50) | BTKSMN1; SMN2KDM4ELMNAMEN1 | |
| SCHEMBL30919805 | 0.87 | BTK (0.48) | BTKALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL31333250 | 0.87 | BTK (0.48) | BTKRPS6KA5MAPK14ADORA1ESR2 | |
| SCHEMBL27262881 | 0.87 | BTK (0.48) | BTKALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL30444276 | 0.87 | KDM4E (0.55) | BTKALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL25820968 | 0.87 | KDM4E (0.55) | BTKALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL30919656 | 0.87 | BTK (0.50) | BTKLMNARPS6KA5MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-4341254-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Dana-Farber Cancer Institute, Inc. (US) | 2024-03-27 | — | — | EP | disclosed |
| WO-2022246025-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-24 | — | — | WO | disclosed |