Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.50 |
| ▸ | AHR | P35869 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 3/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539390 | 0.92 | AHR (0.48) | BTKAHRADORA1LMNANPSR1 | |
| SCHEMBL27262933 | 0.87 | BTK (0.50) | BTKAHRLMNAMAPK13MAPK12 | |
| SCHEMBL30919768 | 0.87 | BTK (0.50) | BTKAHRLMNAMAPK13MAPK12 | |
| SCHEMBL29967741 | 0.87 | BTK (0.52) | BTKADORA1LMNAIDO1MAPK13 | |
| SCHEMBL27177141 | 0.87 | BTK (0.52) | BTKADORA1LMNAIDO1MAPK13 | |
| SCHEMBL30919617 | 0.87 | BTK (0.52) | BTKADORA1LMNAIDO1MAPK13 | |
| SCHEMBL30919805 | 0.84 | BTK (0.48) | BTKLMNARPS6KA5 | |
| SCHEMBL27262881 | 0.84 | BTK (0.48) | BTKLMNARPS6KA5 | |
| SCHEMBL31333250 | 0.84 | BTK (0.48) | BTKADORA1MAPK14RPS6KA5 | |
| SCHEMBL27268385 | 0.81 | BTK (0.53) | BTKADORA1IDO1DHFRNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618755-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |