Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23388894 | 1.00 | DHODH (0.48) | DHODHMEN1GMNNALDH1A1LMNA | |
| SCHEMBL23389039 | 0.87 | MAPT (0.45) | DHODHMEN1GMNNALDH1A1LMNA | |
| SCHEMBL29968260 | 0.87 | MAPT (0.45) | DHODHMEN1GMNNALDH1A1LMNA | |
| SCHEMBL23388887 | 0.84 | MAPT (0.49) | DHODHALDH1A1LMNAPTGS1MAPT | |
| SCHEMBL29888359 | 0.84 | MAPT (0.49) | DHODHALDH1A1LMNAPTGS1MAPT | |
| SCHEMBL23388925 | 0.84 | MAPT (0.52) | DHODHLMNAMAPTTLR7EPHX2 | |
| SCHEMBL31006762 | 0.84 | MAPT (0.52) | DHODHLMNAMAPTTLR7EPHX2 | |
| SCHEMBL22542860 | 0.82 | EPHX2 (0.54) | DHODHMEN1KMT2ATDP1EPHX2 | |
| SCHEMBL18049816 | 0.81 | MAPT (0.55) | DHODHMEN1PTGS1KMT2AMAPT | |
| SCHEMBL4134533 | 0.80 | DHODH (0.62) | DHODHMEN1ALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279368-B | Heteroaryl compounds | 维瓦斯治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115279368-A | Heteroaryl compounds | 维瓦斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |