Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23388887 | 1.00 | MAPT (0.49) | MAPTTLR7FLT3PTGS1ALDH1A1 | |
| SCHEMBL29967939 | 0.84 | DHODH (0.48) | MAPTTLR7FLT3PTGS1ALDH1A1 | |
| SCHEMBL23388894 | 0.84 | DHODH (0.48) | MAPTTLR7FLT3PTGS1ALDH1A1 | |
| SCHEMBL23389039 | 0.83 | MAPT (0.45) | MAPTTLR7FLT3PTGS1ALDH1A1 | |
| SCHEMBL29968260 | 0.83 | MAPT (0.45) | MAPTTLR7FLT3PTGS1ALDH1A1 | |
| SCHEMBL18049816 | 0.83 | MAPT (0.55) | MAPTPTGS1KDREPHX2DHODH | |
| SCHEMBL30323493 | 0.81 | EGLN1 (0.49) | MAPTTLR7KDREGLN1EPHX2 | |
| SCHEMBL23388895 | 0.81 | LMNA (0.58) | MAPTPTGS1ALDH1A1KDREGLN1 | |
| SCHEMBL29968544 | 0.81 | LMNA (0.58) | MAPTPTGS1ALDH1A1KDREGLN1 | |
| SCHEMBL25247975 | 0.81 | DHODH (0.46) | MAPTTLR7ALDH1A1KDRDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279368-B | Heteroaryl compounds | 维瓦斯治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115279368-A | Heteroaryl compounds | 维瓦斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-4061364-A1 | HETEROARYL COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |