Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930395 | 0.81 | CYP1A2 (0.44) | CYP1A2SIGMAR1HPGDMETAP1ACHE | |
| SCHEMBL3546161 | 0.80 | KDM4E (0.34) | CYP1A2 | |
| SCHEMBL3546906 | 0.78 | CYP1A2 (0.32) | CYP1A2 | |
| SCHEMBL15703647 | 0.78 | CYP1A2 (0.46) | CYP1A2SIGMAR1ACHECHRM5ADRA2C | |
| SCHEMBL2998203 | 0.78 | CYP1A2 (0.46) | CYP1A2SIGMAR1ACHECHRM5ADRA2C | |
| SCHEMBL22484358 | 0.77 | CYP1A2 (0.50) | CYP1A2SIGMAR1HPGDMETAP1ACHE | |
| SCHEMBL3001150 | 0.76 | CYP1A2 (0.45) | CYP1A2SIGMAR1HSD11B1 | |
| SCHEMBL15330108 | 0.76 | CYP1A2 (0.61) | CYP1A2SIGMAR1HPGD | |
| SCHEMBL29028954 | 0.74 | CYP1A2 (0.48) | CYP1A2SIGMAR1 | |
| SCHEMBL3003348 | 0.74 | CYP1A2 (0.48) | CYP1A2SIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |