Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871252 | 1.00 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBGRIN2BGRIN1 | |
| SCHEMBL29968313 | 0.91 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBGRIN2BGRIN1 | |
| SCHEMBL29968030 | 0.84 | CNR2 (0.42) | HPGDCNR2PARP1ACMSD | |
| SCHEMBL29967526 | 0.82 | CHRM1 (0.45) | PIK3CDPIK3CAPIK3CBCNR2PARP1 | |
| SCHEMBL29967696 | 0.81 | FFAR4 (0.41) | PIK3CDPIK3CAPIK3CBCNR2PARP1 | |
| SCHEMBL29967862 | 0.81 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBCNR2ACMSD | |
| SCHEMBL29968037 | 0.80 | PARP1 (0.39) | HPGDCNR2PARP1ACMSD | |
| SCHEMBL29968177 | 0.80 | PTGS2 (0.39) | PIK3CDPIK3CAPIK3CBCNR2HSD17B10 | |
| SCHEMBL29967941 | 0.79 | PIK3CD (0.36) | PIK3CDPIK3CAPIK3CBCNR2PARP1 | |
| SCHEMBL29967810 | 0.78 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBCNR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260165-B | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2024-08-06 | — | — | CN | disclosed |
| CN-115260165-A | Benzo nitrogen-containing five-membered heterocyclic compound and synthesis and application thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | disclosed |