Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692168 | 1.00 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL14535364 | 1.00 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL29488726 | 1.00 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL2187996 | 1.00 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL2495651 | 1.00 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL29968494 | 0.98 | CA2 (0.54) | CA2MAPK1CA1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL30674035 | 0.98 | CA2 (0.54) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL2152713 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL29712267 | 0.95 | CA2 (0.56) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL9142874 | 0.91 | CA2 (0.67) | CA2MAPK1CA1MAPTSLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |