Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23763096 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL23763177 | 0.86 | KRAS (0.36) | KRASKMT2ACYP2D6CYP1A2 | |
| SCHEMBL855780 | 0.78 | CYP1A2 (0.55) | CYP2C19MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL23763097 | 0.77 | MAP3K12 (0.43) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL23763095 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL29968245 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL29969097 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL23763390 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL29969109 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HPGDUSP2HIF1A | |
| SCHEMBL23763276 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HPGDUSP2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151534-B | Inhibitors of interleukin-1 receptor associated kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof and methods of use thereof | 南京药石科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-115151534-A | Inhibitors of interleukin-1 receptor-related kinase (IRAK)/FMS-like receptor tyrosine kinase (FLT 3), pharmaceutical products thereof, and methods thereof | 南京药石科技股份有限公司 | 2022-10-04 | — | — | CN | disclosed |